Use node-bindings.

lib/sqlite3.js

-var sqlite3 = module.exports = exports = require('./node_sqlite3.node');
+var sqlite3 = module.exports = exports = require('bindings')('node_sqlite3.node');
 var path = require('path');
 var util = require('util');
 var EventEmitter = require('events').EventEmitter;

package.json

@@ -26,6 +26,9 @@
         "type": "git",
         "url": "git://github.com/developmentseed/node-sqlite3.git"
     },
+    "dependencies": {
+        "bindings": "*"
+    },
     "devDependencies": {
         "step": "0.0.4",
         "expresso": "*"